type and form of vaccine:
This vaccine is a sterile combination of diphtheria and tetanus toxoids (DT) absorbed on aluminum phosphate (adjuvant).
Vaccine compositions:
One dose of the vaccine (0.5 ml) contains:
Diphtheria toxoid       ≤ 30 Lf
Tetanus toxoid    ≤ 25 Lf
Aluminum phosphate (based on aluminum ions)       max. 1.25 milligrams
Thiomersal (as preservative)      max. 50 micrograms
Indication:
This vaccine is used for active immunization against diphtheria and tetanus in infants and children under the age of 6 years, who cannot receive the DTP vaccine.
Administration route and dosage:
After stirring the vaccine, aseptically inject 0.5 ml intramuscularly.
Recommended vaccination program:
Vaccination should be performed according to the guidelines of the National Immunization Committee. This vaccine is recommended for children who cannot receive the DTP vaccine.
Use during pregnancy and lactation:
This vaccine is not intended for individuals over 6.
Contraindications:
A comprehensive study about the drug interactions of this product has not been performed. However, administering this vaccine with other vaccines covered by the National Immunization Committee is permissible on the condition that they are injected in different locations, and different syringes are used.
Side effects:

• Topical Reactions: redness and inflammation in the site of injection
• General Reactions: fever, headache, sometimes rashes and in rare cases, anaphylactic reactions

Drug interactions:
A comprehensive study about the medicinal interactions of this product has not been performed. However, administering this vaccine with other vaccines covered by the National Immunization Committee is permissible on the condition that they are injected in different locations, and different syringes are used.
Precautions and warnings:

• Shake the vaccine vial (or ampoule) gently before every injection until it is uniformed thoroughly
• If one or more doses of vaccine have been removed during an immunization session, vaccine may be used up to a month if cold chain and aseptic conditions are observed
• Do not use vaccine after the expiration date
• Prevent vaccine from freezing. Do not use if frozen
• Observe aseptic conditions during injection
• If a history of fever and febrile convulsions (unrelated to the vaccine) exist, it is suggested to monitor body temperature for 48 hours after vaccination, and treat with Anti fever medications
• Treatment with medications weakening the immune system, or immunodeficiency illnesses, causes reduction of immune response
• In case of occurrence of anaphylactic reactions, injection of adrenaline under a physician's supervision is recommended 

Safe disposal of waste or partially used vaccines:
Single-use equipment used, and empty vaccine vials should be placed in the sharp-equipment container, and sterilized correctly (autoclave, burning, or using appropriate chemicals), and then buried hygienically.
Storage:
This vaccine should be stored and transported at 2 to 8°C and away from sunlight. In these conditions, it may be used until the expiration date written on the label.
Packaging:
This vaccine is distributed in 7-ml (14-dose) vials and single-dose ampoules.
Last reviewed:
22.12.2018
References:
1-    schedule and guidelines approved by the National Immunization Committee, 1394
2-    Martindale, the complete drug reference, 39th edition.
3-    WHO Technical Report Series No. 980